Compare and contrast the similarities and differences between
the drugs ibuprofen and paracetamol with respect to
pharmacokinetics and pharmacodynamics.
Order Description
Use resources such as journal articles medical and scientific
text books or scientific web based resources (e.g. NIH website
American Heart Association website). DO NOT use websites that
include .com in their web address as they are usually commercial
websites that are targeted at promoting a particular viewpoint
related to economic gain.
For your essay:
1. Provide a brief descriptive title of no more than 10
words. Include in the title the drug group that your chosen pair
belong to.
2. Introduce the drugs and specify their actions and
indications;
3. Describe the pharmacokinetics of each drug comparing the
following:
a. How is the drug administered?
b. How is the drug absorbed?
c. What is the bioavailability and half-life of the drug?
d. How is it distributed in the body?
e. How is the drug metabolised?
f. How is the drug excreted?
4. Detail and compare the pharmocodynamics of the drugs.
Include the following information:
a. What is the mechanism of action of the drug? If this
currently unknown what is it thought to be?
b. What is the molecular target of the drug?
c. What is the effect of the drug after it binds to its
molecular target. Remember you are comparing the two drugs so a
step by step comparison is appropriate here.
d. Explain how the mechanism of action of the drug is related
to its side effects.
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